Course

PCR: Basic Principles

COURSE 2025A
Participants:

Jaider Arnulfo Guzmán González

Molecule: HSP70, Leishmania brazilienzis, XM_001566275.1

Ahadini, S. N., Tyasningsih, W., Effendi, M. H., Khairullah, A. R., Kusala, M. K. J., Fauziah, I., Latifah, L., Moses, I. B., Yanestria, S. M., Fauzia, K. A., Kurniasih, D. A. A., & Wibowo, S. (1970). Molecular detection of blaTEM-encoding genes in multidrug-resistant Escherichia coli from cloacal swabs of ducks in Indonesia farms. Open Veterinary Journal. https://doi.org/10.5455/OVJ.2025.v15.i1.8

Danna Isabella Manrique Tovar

Molecule: HSP70, Ovis aries, NM_001267874.1

Azarm A, Dalimi A, Mohebali M, Mohammadiha A, Pirestani M, Zarei Z, Zahraei-Ramazani A. Molecular Identification of Leishmania infantum kDNA in Naturally Infected Dogs and Their Fleas in an Endemic Focus of Canine Visceral Leishmaniasis in Iran. J Arthropod Borne Dis. 2022 Sep 30;16(3):243-250. doi: 10.18502/jad.v16i3.12041.

Nicole Dallana García Aviles

Molecule: ACTB, Homo sapiens, NM_001101.5 

Matos-Rodrigues, G. E., Masseron, C. C., Silva, F. J. M. D. A., Frajblat, M., Moreira, L. O., & Martins, R. A. P. (2020). PCR-based detection of Helicobacter spp. in animal facilities of a University in Rio de Janeiro, Brazil. Anais Da Academia Brasileira de Ciencias, 92(4), e20191517. https://doi.org/10.1590/0001-3765202020191517

Silvia Fernanda Campos Hernández 

Molecule: EF-1 alpha, Sus scrofa, NM_001097418.2 

Sheet, O. H. (2022). Molecular detection of mecA gene in methicillin-resistant Staphylococcus aureus isolated from dairy mastitis in Nineveh governorate, Iraq. Iraqi Journal of Veterinary Sciences, 36(4), 939–943. https://doi.org/10.33899/ijvs.2022.132643.2115

Santiago Gamboa Espinosa 

Molecule: Tp53, Canis lupus familiaris, NM_001389218.1 

Tan, C. Y., Thanawongnuwech, R., Arshad, S. S., Hassan, L., Lee, C. Y., Low, S. E., … & Ooi, P. T. (2023). First molecular detection of Porcine circovirus type 4 (PCV4) in Malaysia. https://doi.org/10.47665/tb.40.3.005

Dilan Paez Gutierrez 

Molecule: IFNT2, Bos taurus, NM_001015511.4 

Osorio-Muñoz K. & Rondón-Barragan, I. S. Molecular detection of Mycoplasma spp. and its associated risk factors in domestic cats in the city of Ibagué, Tolima. The Thai Journal of Veterinary Medicine, 54(2), 263-267. https://doi.org/10.56808/2985-1130.3724

Anderson Santiago Leyva Ardila 

Molecule: CRP, Gallus gallus, NM_001039564.2

Feronato, C., Leme, R. A., Diniz, J. A., Agnol, A. M. D., Alfieri, A. F., & Alfieri, A. A. (2018). Development and evaluation of a nested-PCR assay for Senecavirus A diagnosis. Tropical animal health and production, 50, 337-344. https://doi.org/10.1007/s11250-017-1436-z.

Laura Tatiana Díaz Molina 

Molecule: AQP7, Bos taurus, NM_001076378.2 

Cho, J., Jeong, S., Kim, M., Cho, W. S., Kim, D., & Park, C. (2024). Loop-mediated isothermal amplification polymerase chain reaction in place of a modified Knott test in screening dogs for heartworm (Dirofilaria immitis) infection combined with antigen detection test. American Journal Of Veterinary Research, 85(9). https://doi.org/10.2460/ajvr.24.02.0027

Laura Chacón Tique 

Molecule: Raf-1, Homo sapiens, NM_001354695.3 

Koshino, A., Goto-Koshino, Y., Setoguchi, A., Ohno, K., & Tsujimoto, H. (2016). Mutation of p53 gene and its correlation with the clinical outcome in dogs with lymphoma. Journal of Veterinary Internal Medicine, 30(1), 223–229. https://doi.org/10.1111/jvim.13807

Natalia Chacón Tique 

Molecule: AQP5, Bos taurus, NM_001191160.1 

Ayene, Y. Y., Mohebali, M., Hajjaran, H., Akhoundi, B., Shojaee, S., Rahimi-Foroushani, A., Afshar, M. J. A., & Zarei, Z. (2021). A comparative study of nested-PCR and direct agglutination test (DAT) for the detection of Leishmania infantum infection in symptomatic and asymptomatic domestic dogs. BMC Research Notes, 14(1). https://doi.org/10.1186/s13104-021-05654-0

Juan David Mendoza Cañón 

Molecule: 18s, Hepatozoon canis, MK757814.1 

Yadav, J. P., Das, S. C., Dhaka, P., Mukhopadhyay, A. K., Chowdhury, G., Naskar, S., & Malik, S. S. (2018). Pulsed-field gel electrophoresis of enterotoxic Clostridium perfringens type A isolates recovered from humans and animals in Kolkata, India. International Journal of Veterinary Science and Medicine, 6(1), 123–126. https://doi.org/10.1016/j.ijvsm.2017.11.002

Juan David Mendez Cuellar 

Molecule: GATA3, Bos taurus, NM_001076804.1 

Dehuri, M., Panda, M., Sahoo, N., Mohanty, B., & Behera, B. (2021). Nested PCR assay for detection of Theileria annulata in Hyalomma anatolicum infesting cattle from coastal Odisha, India. Animal Biotechnology, 33(6), 1229-1234. https://doi.org/10.1080/10495398.2021.1885427

Catalina Lapuente Chala 

Molecule: Gfap, Danio rerio, NM_131373.2

Ekawasti F, Nurcahyo RW, Nashrulloh MF, Priyowidodo D, Prastowo J. Development of a multiplex polymerase chain reaction technique for detection and discrimination of Eimeria spp. in cattle in Indonesia. Vet World. 2022 Apr;15(4):975-980. https://doi.org/doi:10.14202/vetworld.2022.975-980.

Jeison Alfonso Yaima Yate 

Molecule: Plasmepsin V, Babesia bovis, 5479544 

Saito, K., Kimata, K., Watahiki, M., Isobe, J., Kanatani, J. I., Ikeda, K., Takeuchi, T., Matsuzaki, C., & Oishi, K. (2025). Investigation of an Outbreak of Clostridium perfringens in Toyama, Japan, 2023 Using Single-Nucleotide Polymorphism Analysis for Genotyping. Japanese journal of infectious diseases, 78(1), 47–50. https://doi.org/10.7883/yoken.JJID.2024.189

Here you will find a supportive videographic material for the course. Please enjoy, suscribe to LIBM Youtube channel for more content.

These videographic material is associated with the Course of Applied Molecular Biology from the Laboratory of Immunology and Molecular Biology (Universidad del Tolima) Project “IDENTIFICACIÓN DE BIOTIPO BOVINO, MEDIANTE BIOTECNOLOGÍA MOLECULAR, ADAPTABLE AL CAMBIO CLIMÁTICO EN EL DEPARTAMENTO DE CÓRDOBA, CARIBE”, BPIN code 2016000100026 of the Sistema General de Regalías

Basic Search on NCBI

PCR basic concepts

Primer design

Running a Endpoint PCR

Electrophoresis (Agarose)

PAGE (PolyAcrylamide Gel Electrophoresis)